SCHEMBL27800484

SCHEMBL27800484

Brc1ccc2[c]c3ccccc3c(-c3ccccc3)c2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DCLK1 O15075 1/20 0.39
PRKD3 O94806 1/20 0.39
MAP4K4 O95819 1/20 0.39
CHEK2 O96017 1/20 0.39
CSF1R P07333 1/20 0.39
FER P16591 1/20 0.39
CDK2 P24941 1/20 0.39
MARK3 P27448 1/20 0.39
FLT4 P35916 1/20 0.39
FLT3 P36888 1/20 0.39
MAPK9 P45984 1/20 0.39
CSNK1D P48730 1/20 0.39
CLK2 P49760 1/20 0.39
CSNK2A1 P68400 1/20 0.39
CSNK1G2 P78368 1/20 0.39
MAP4K2 Q12851 1/20 0.39
STK3 Q13188 1/20 0.39
CAMK2B Q13554 1/20 0.39
CAMK2G Q13555 1/20 0.39
DYRK1A Q13627 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27849808 0.90 ALDH1A1 (0.38) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL1820644 0.83 ACHE (0.45) ALDH1A1MAPK1KDM4EMAPTACHE
SCHEMBL15453046 0.79 ACHE (0.42) ALDH1A1MAPK1MAPTACHEESR1
SCHEMBL30136959 0.77 ALDH1A1 (0.46) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL389776 0.77 ALDH1A1 (0.46) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL28762446 0.77 ACHE (0.35) ALDH1A1MAPK1KDM4EMAPTMEN1
SCHEMBL3875883 0.76 ALDH1A1 (0.38) ALDH1A1MEN1KMT2AACHEESR1
SCHEMBL4584724 0.75 ALDH1A1 (0.48) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL824275 0.75 ALDH1A1 (0.48) DCLK1PRKD3MAP4K4CHEK2CSF1R
SCHEMBL28762429 0.75 ESR1 (0.39) MAP4K4ALDH1A1KDM4EMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101679855-B Novel materials for organic electroluminescent devices MERCK PATENT GMBH 2013-03-27 CN disclosed
CN-101679855-A The novel material that is used for organic electroluminescence device MERCK PATENT GMBH 2010-03-24 CN disclosed