Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 6/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15453046 | 0.95 | ACHE (0.42) | ACHEESR1ESR2MAPTLMNA | |
| SCHEMBL3875883 | 0.87 | ALDH1A1 (0.38) | ACHEESR1ESR2ALDH1A1EGFR | |
| SCHEMBL28762429 | 0.86 | ESR1 (0.39) | ACHEESR1ESR2MAPTLMNA | |
| SCHEMBL22635772 | 0.85 | MAOA (0.39) | ACHEESR1ESR2ALDH1A1 | |
| SCHEMBL15453009 | 0.84 | ACHE (0.35) | ACHEESR1ESR2MAPTLMNA | |
| SCHEMBL28762446 | 0.84 | ACHE (0.35) | ACHEESR1ESR2MAPTLMNA | |
| SCHEMBL6759020 | 0.84 | CYP2A6 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL27800484 | 0.83 | DCLK1 (0.39) | ACHEESR1ESR2MAPTALDH1A1 | |
| SCHEMBL27849808 | 0.83 | ALDH1A1 (0.38) | ACHEESR1ESR2MAPTALDH1A1 | |
| SCHEMBL21295977 | 0.82 | IMPDH2 (0.49) | MAPTLMNAALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964502-A | Method for asymmetric catalytic synthesis of alpha-aminoketone | 南开大学 | 2024-05-03 | — | — | CN | claimed |
| CN-117800900-A | Polysubstituted chiral bicyclo [2.1.1] hexane compound and synthesis method thereof | 河南师范大学 | 2024-04-02 | — | — | CN | claimed |
| CN-115057762-B | Aggregation-resistant induced quenching type rigid Gemini fluorescent amphiphilic molecule and synthesis method thereof | 武汉大学 | 2023-09-08 | — | — | CN | claimed |
| CN-103534331-B | Naphthalene derivatives, comprise its organic material and comprise its organic electroluminescent device | 大州电子材料株式会社 | 2016-06-08 | — | — | CN | claimed |
| CN-103805167-B | Organic blue luminescent material and its preparation method and application | Jilin Optical and Electronic Materials Co., Ltd. (CN) | 2015-12-02 | — | — | CN | claimed |
| US-9024304-B2 | Naphthalene derivative, organic material including the same, and organic electroluminescent device including the same | DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) | 2015-05-05 | — | — | US | claimed |
| US-9006503-B2 | Organic electroluminescence devices containing substituted benzo[C]phenanthrenes | MERCK PATENT GMBH (DE) | 2015-04-14 | — | — | US | claimed |
| US-20140299849-A1 | NAPHTHALENE DERIVATIVE, ORGANIC MATERIAL INCLUDING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) | 2014-10-09 | — | — | US | claimed |
| CN-103805167-A | Organic blue luminescent material, and preparation method and application thereof | JILIN OPTICAL & ELECTRONIC MATERIALS CO LTD | 2014-05-21 | — | — | CN | claimed |
| EP-2692823-A2 | NAPHTHALENE DERIVATIVES, ORGANIC MATERIAL USING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | Dae Joo Electronic Materials Co., Ltd. (KR) | 2014-02-05 | — | — | EP | claimed |
| CN-103534331-A | Naphthalene derivatives, organic material using same, and organic electroluminescent device using same | DAE JOO ELECTRONIC MAT CO LTD | 2014-01-22 | — | — | CN | claimed |
| US-7482490-B2 | Amine compound having fluorene group as framework, process for producing the amine compound, and use of the amine compound | TOSOH CORPORATION (JP) | 2009-01-27 | — | — | US | claimed |
| US-20080194878-A1 | Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound | TOSOH CORPORATION (JP) | 2008-08-14 | — | — | US | claimed |
| EP-1752440-A1 | AMINE COMPOUND HAVING FLUORENE GROUP AS FRAMEWORK, PROCESS FOR PRODUCING THE AMINE COMPOUND, AND USE OF THE AMINE COMPOUND | Tosoh Corporation (JP) | 2007-02-14 | — | — | EP | claimed |
| CN-1263825-C | Liquid crystal orientation agent, formation method of liquid crystal orientation membrane and liquid crystal display unit | JSR CORP (JP) | 2006-07-12 | — | — | CN | claimed |
| CN-114315742-B | Fluorene-containing compound and application thereof | 湖北尚赛光电材料有限公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-118221708-A | Organic electroluminescent material and device | 环球展览公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | TOSOH CORPORATION | 2004-06-10 | — | — | US | disclosed |
| EP-1400578-A1 | Electrolumisescent 9,9-bis(4-amino)-1,1'-biphenyl)fluorene derivatives | Tosoh Corporation (JP) | 2004-03-24 | — | — | EP | disclosed |
| CN-1442466-A | Liquid crystal orientation agent, formation method of liquid crystal orientation membrane and liquid crystal display unit | JSR CORP (JP) | 2003-09-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110958-A1 | Novel arylamine derivatives having fluorene skeleton, synthetic intermediates thereof, processes of producing those, and organic electrolumivescene devices | AHR, NAT1, AR | ACHE 3669/4885ESR1 139/4885ESR2 38/4885 |
| US-20080194878-A1 | Amine Compound Having Fluorene Group as Framework, Process for Producing the Amine Compound, and Use of the Amine Compound | TAAR1, SLC18A1, ADRB2 | ACHE 2539/4885ESR1 521/4885ESR2 603/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.