Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | CHAT | P28329 | 3/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20298611 | 0.93 | ALDH1A1 (0.46) | HDAC8ALDH1A1CYP2A6CHATKDM4E | |
| SCHEMBL3475924 | 0.93 | ALDH1A1 (0.46) | HDAC8ALDH1A1CYP2A6CHATKDM4E | |
| SCHEMBL7571439 | 0.87 | ALDH1A1 (0.41) | HDAC8ALDH1A1CYP2A6CHATKDM4E | |
| SCHEMBL4154334 | 0.86 | ALDH1A1 (0.36) | HDAC8ALDH1A1CYP2A6CHATSTS | |
| SCHEMBL658342 | 0.84 | HDAC8 (0.64) | HDAC8ALDH1A1CHATACHEKDM4E | |
| SCHEMBL28596843 | 0.83 | ALDH1A1 (0.41) | HDAC8ALDH1A1CYP2A6STSKDM4E | |
| SCHEMBL1425978 | 0.82 | — | — | |
| Sulfuric Acid SCHEMBL7787999 | 0.81 | CHAT (0.52) | HDAC8ALDH1A1CYP2A6CHATKDM4E | |
| SCHEMBL11032707 | 0.81 | CHAT (0.67) | ALDH1A1CHATKDM4EHPGDCYP2C19 | |
| SCHEMBL2779790 | 0.81 | HDAC8 (0.49) | HDAC8ALDH1A1CYP2A6CHATACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7767381-B2 | Photosensitive resin composition, and photosensitive film and stencil for screen printing using the photosensitive composition | MURAKAMI CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090099275-A1 | Photosensitive Resin Composition, and Photosensitive Film and Stencil for Screen Printing Using the Photosensitive Composition | MURAKAMI CO., LTD. (JP) | 2009-04-16 | — | — | US | disclosed |
| EP-2019128-A1 | PHOTOSENSITIVE RESIN COMPOSITION AND PRODUCED THEREFROM, PHOTOSENSITIVE FILM AND STENCIL FOR SCREEN PRINTING | Murakami Co., Ltd. (JP) | 2009-01-28 | — | — | EP | disclosed |
| EP-1817379-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | The Procter and Gamble Company (US) | 2007-08-15 | — | — | EP | disclosed |
| US-20070033742-A1 | Pyrazole azomethines and colorants containing these compounds | PROCTER & GAMBLE COMPANY, THE | 2007-02-15 | — | — | US | disclosed |
| WO-2006060564-A2 | PYRAZOLE AZOMETHINES AND COLORANTS CONTAINING THESE COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070033742-A1 | Pyrazole azomethines and colorants containing these compounds | KRT18, NOX5, TUBB3 | ACHE 1916/4885HDAC8 1274/4885ALDH1A1 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.