Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780056 | 0.86 | HDAC8 (0.41) | ALDH1A1CYP2A6HDAC8CHATSTS | |
| SCHEMBL20298611 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP2A6HDAC8CHATLMNA | |
| SCHEMBL3475924 | 0.83 | ALDH1A1 (0.46) | ALDH1A1CYP2A6HDAC8CHATLMNA | |
| SCHEMBL28596843 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP2A6HDAC8STSLMNA | |
| SCHEMBL7571439 | 0.77 | ALDH1A1 (0.41) | ALDH1A1CYP2A6HDAC8CHATLMNA | |
| SCHEMBL29053037 | 0.77 | RAD52 (0.36) | ALDH1A1KCNH2CHATLMNAMAPT | |
| SCHEMBL5483989 | 0.74 | HDAC8 (0.64) | ALDH1A1CYP2A6HDAC8CA12CA1 | |
| Sulfuric Acid SCHEMBL7787999 | 0.73 | CHAT (0.52) | ALDH1A1CYP2A6HDAC8CHATLMNA | |
| SCHEMBL2779790 | 0.72 | HDAC8 (0.49) | ALDH1A1CYP2A6HDAC8CHATLMNA | |
| Paraquat SCHEMBL3676472 | 0.71 | SLC6A4 (0.48) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897858-A1 | COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER AND AN ALKALINE AGENT AND/OR AN AMINO ALKOXYSILANE DERIVATIVE AND TREATMENT METHOD IMPLEMENTING THE COMPOSITION | L'OREAL (FR) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127230-A1 | COMPOSITION COMPRISING A MODIFIED PHOTO-DIMERIZABLE POLYMER AND AN ALKALINE AGENT AND/OR AN AMINO ALKOXYSILANE DERIVATIVE AND TREATMENT METHOD IMPLEMENTING THE COMPOSITION | L'OREAL (FR) | 2020-06-25 | — | — | WO | disclosed |
| EP-2654712-B1 | STERILE LIQUID COMPOSITION FOR FILLING WRINKLES | L'ORÉAL (FR) | 2017-02-22 | — | — | EP | disclosed |
| EP-2654712-A2 | STERILE LIQUID COMPOSITION FOR FILLING WRINKLES | L'Oréal (FR) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085835-A2 | STERILE LIQUID COMPOSITION FOR FILLING WRINKLES | L'OREAL (FR) | 2012-06-28 | — | — | WO | disclosed |
| EP-1767597-B1 | Ink-jet ink, ink-jet ink set and ink-jet recording method | KONICA MINOLTA HOLDINGS INC (JP) | 2009-06-17 | — | — | EP | disclosed |
| EP-1767597-A1 | Ink-jet ink, ink-jet ink set and ink-jet recording method | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20070064050-A1 | Ink-jet ink, ink-jet ink set and ink-jet recording method | KONICA MINOLTA HOLDINGS, INC. (JP) | 2007-03-22 | — | — | US | disclosed |