Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29465780 | 0.95 | ESR1 (0.55) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL69822 | 0.95 | ESR1 (0.55) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL5013862 | 0.84 | TSHR (0.42) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL28494827 | 0.82 | ESR1 (0.47) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL27277 | 0.80 | ESR1 (1.00) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL8031149 | 0.80 | ESR1 (1.00) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| Methane SCHEMBL16667289 | 0.78 | ESR1 (0.95) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| Phenol SCHEMBL29851136 | 0.78 | ESR1 (0.95) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL9243349 | 0.78 | ESR1 (0.70) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL30084848 | 0.77 | KIF11 (0.47) | ESR1ESR2CYP3A4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2218579-A1 | Improved method for manufacturing a laminated multi-layer film | Bayer MaterialScience AG (DE) | 2010-08-18 | — | — | EP | disclosed |