SCHEMBL28494827

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29465780	0.86	ESR1 (0.55)	ESR1ESR2CYP3A4ALDH1A1HPGD
	SCHEMBL69822	0.86	ESR1 (0.55)	ESR1ESR2CYP3A4ALDH1A1HPGD
	SCHEMBL2780078	0.82	ESR1 (0.65)	ESR1ESR2CYP3A4ALDH1A1HPGD
	SCHEMBL4191295	0.81	RAB9A (0.45)	ALDH1A1HPGDCYP1A2MEN1KMT2A
	SCHEMBL28507099	0.79	CYP1A2 (0.50)	ALDH1A1HSD17B10TSHRCYP1A2KMT2A
	SCHEMBL10771644	0.75	ESR1 (0.43)	ESR1ESR2CYP3A4ALDH1A1HPGD
	SCHEMBL23916639	0.74	ALDH1A1 (0.44)	CYP3A4ALDH1A1HPGDHSD17B10TSHR
	SCHEMBL4196806	0.74	ESR1 (0.75)	ESR1ESR2CYP3A4ALDH1A1HPGD
	SCHEMBL30084848	0.72	KIF11 (0.47)	ESR1ESR2CYP3A4ALDH1A1HPGD
	SCHEMBL343839	0.72	ESR1 (0.71)	ESR1ESR2CYP3A4ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.