Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23878080 | 0.88 | ALDH1A1 (0.40) | KMT2AHSD17B10CYP3A4TDP1TAAR1 | |
| SCHEMBL346045 | 0.83 | TSHR (0.38) | KMT2AHSD17B10CYP3A4TDP1NPC1 | |
| SCHEMBL8758644 | 0.80 | MEN1 (0.42) | MAOAKMT2AATMHSD17B10NPC1 | |
| SCHEMBL27887991 | 0.80 | MEN1 (0.42) | MAOAKMT2AATMHSD17B10NPC1 | |
| SCHEMBL1697770 | 0.79 | PTPRC (0.45) | MAOAKMT2ATLR9ATMHSD17B10 | |
| SCHEMBL27874732 | 0.78 | ADORA2A (0.36) | KMT2AHSD17B10CYP3A4TDP1TAAR1 | |
| SCHEMBL258568 | 0.78 | ALDH1A1 (0.44) | TDP1ALDH1A1TP53TSHRPOLB | |
| SCHEMBL28067626 | 0.78 | CYP19A1 (0.53) | MAOAKMT2ATLR9ATMHSD17B10 | |
| SCHEMBL17643517 | 0.78 | APP (0.38) | MAOA | |
| SCHEMBL28266726 | 0.77 | ALDH1A1 (0.38) | MAOAKMT2ATLR9ATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101962324-A | Method for preparing 3,5-difluoro-4'-vinyl biphenyl-4-amine | UNIV ZHEJIANG | 2011-02-02 | — | — | CN | claimed |
| CN-101962324-A | Method for preparing 3,5-difluoro-4'-vinyl biphenyl-4-amine | UNIV ZHEJIANG | 2011-02-02 | — | — | CN | disclosed |