Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 9/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117513 | 0.87 | ITGAV (0.39) | CASP1ITGAVITGB3ITGA2BFDPS | |
| SCHEMBL27801369 | 0.83 | CASP1 (0.36) | CASP1ITGAVITGB3ITGA2BFDPS | |
| SCHEMBL2116269 | 0.77 | FDPS (0.39) | FDPSGAAFNTAPGGT1B | |
| Hydrochloric Acid SCHEMBL2116377 | 0.76 | FDPS (0.38) | FDPSGAAFNTAPGGT1B | |
| SCHEMBL2119125 | 0.72 | FDPS (0.42) | FDPSGAAFNTAPGGT1B | |
| Ammonia Solution, Strong SCHEMBL2117519 | 0.72 | GAA (0.36) | FDPSGAA | |
| Hydrochloric Acid SCHEMBL2119121 | 0.71 | FDPS (0.42) | FDPSGAAFNTAPGGT1B | |
| SCHEMBL2116667 | 0.70 | CA12 (0.38) | CASP1FDPSFNTAPGGT1B | |
| SCHEMBL2116709 | 0.70 | HDAC8 (0.39) | FDPSGAA | |
| SCHEMBL2115818 | 0.70 | KYNU (0.45) | CASP1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959865-A | Quinolines as farnesyl pyrophosphate synthase inhibitor | NOVARTIS AG | 2011-01-26 | — | — | CN | claimed |
| CN-101959865-A | Quinolines as farnesyl pyrophosphate synthase inhibitor | NOVARTIS AG | 2011-01-26 | — | — | CN | disclosed |