Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | F3 | P13726 | 1/20 | 0.48 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18469285 | 0.98 | ALDH1A1 (0.52) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL17135323 | 0.98 | ALDH1A1 (0.52) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL6921845 | 0.98 | ALDH1A1 (0.52) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL11529583 | 0.83 | ALDH1A1 (0.50) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL2377741 | 0.82 | TBXAS1 (0.49) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL991179 | 0.82 | TBXAS1 (0.49) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL13570303 | 0.81 | TBXAS1 (0.46) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL27594324 | 0.81 | ALDH1A1 (0.57) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL28830747 | 0.81 | ALDH1A1 (0.57) | TBXAS1ALDH1A1APPGAAHCAR3 | |
| SCHEMBL10193816 | 0.79 | TBXAS1 (0.57) | TBXAS1ALDH1A1APPGAAHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952284-A | Novel tetracyclic compounds | MEDIVATION TECHNOLOGIES INC | 2011-01-19 | — | — | CN | disclosed |