SCHEMBL28830747

SCHEMBL28830747

CC=C(O)c1cccnc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
APP P05067 1/20 0.57
GAA P10253 1/20 0.57
HCAR3 P49019 1/20 0.57
HCAR2 Q8TDS4 1/20 0.57
F7 P08709 1/20 0.50
F3 P13726 1/20 0.50
SARM1 Q6SZW1 1/20 0.50
SIRT2 Q8IXJ6 1/20 0.50
SIRT6 Q8N6T7 1/20 0.50
SIRT1 Q96EB6 1/20 0.50
SIRT3 Q9NTG7 1/20 0.50
SIRT5 Q9NXA8 1/20 0.50
SIRT4 Q9Y6E7 1/20 0.50
CYP11B2 P19099 2/20 0.48
PLOD2 O00469 1/20 0.48
CYP19A1 P11511 1/20 0.48
TBXAS1 P24557 4/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27594324 1.00 ALDH1A1 (0.57) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL18469285 0.83 ALDH1A1 (0.52) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL17135323 0.83 ALDH1A1 (0.52) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL6921845 0.83 ALDH1A1 (0.52) ALDH1A1APPGAAHCAR3HCAR2
Ammonia Solution, Strong SCHEMBL27802137 0.81 TBXAS1 (0.50) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL20027305 0.80 TBXAS1 (0.50) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL8228555 0.79 MKNK1 (0.64) ALDH1A1GAACYP11B2CYP19A1CYP1A2
SCHEMBL24579551 0.77 ALDH1A1 (0.67) ALDH1A1APPGAAHCAR3HCAR2
SCHEMBL27812729 0.77
SCHEMBL15131514 0.76 POLB (0.51) ALDH1A1APPGAAHCAR3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114361456-B Water-based functional ion-conducting binder for lithium battery, preparation method and application 中国科学院化学研究所 2023-05-05 CN claimed
CN-114957086-A Synthesis method and application of N-trifluoromethylsulfonyl phthalimide 杭州师范大学 2022-08-30 CN disclosed