Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.38 |
| ▸ | CPN1 | P15169 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25058914 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7457093 | 0.78 | SHBG (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL121101 | 0.71 | CPN1 (0.39) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL10206052 | 0.71 | CPN1 (0.39) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL18872565 | 0.71 | CPN1 (0.35) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL24383385 | 0.70 | CPN1 (0.42) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| Hydrochloric Acid SCHEMBL149567 | 0.70 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL27293691 | 0.69 | OPRD1 (0.33) | CPN1CPB2OPRD1 | |
| SCHEMBL14246963 | 0.69 | CPN1 (0.41) | SLC6A2SLC6A4SLC6A3CPN1CPB2 | |
| SCHEMBL22066364 | 0.69 | CPN1 (0.41) | SLC6A2SLC6A4SLC6A3CPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952286-A | Bicyclic derivatives for use in the treatment of androgen receptor associated conditions | ASTRAZENECA AB | 2011-01-19 | — | — | CN | disclosed |