Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | KDM5C | P41229 | 2/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4B | O94953 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29642415 | 0.84 | CCNC (0.50) | CDK8CCNCKDM5CKDM5BKDM4B | |
| SCHEMBL1569241 | 0.84 | CCNC (0.50) | CDK8CCNCKDM5CKDM5BKDM4B | |
| SCHEMBL3863943 | 0.82 | CCNC (0.49) | CDK8CCNCKDM5CKDM5BKDM4B | |
| Hydrochloric Acid SCHEMBL14759172 | 0.82 | CCNC (0.49) | CDK8CCNCKDM5CKDM5BKDM4B | |
| Butyramide SCHEMBL27747635 | 0.78 | LMNA (0.42) | CDK8CCNCKDM5CKDM5BKDM5A | |
| SCHEMBL2257182 | 0.78 | RAB9A (0.40) | RAB9ANPC1CDK8CCNCSMARCA2 | |
| SCHEMBL5566822 | 0.76 | CYP1A2 (0.46) | MBOAT4KDM5CKDM5BKDM5AKDM5D | |
| SCHEMBL6504215 | 0.76 | LOX (0.48) | CDK8CCNCKDM5CKDM5BKDM5A | |
| Acetonitrile SCHEMBL21495142 | 0.75 | CYP11B1 (0.44) | CDK8CCNCKDM5CKDM5BKDM4B | |
| SCHEMBL7668183 | 0.74 | CYP1A2 (0.47) | MBOAT4KDM5CKDM5BKDM5AKDM5D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679418-A | [2,6] naphthyridines compounds as protein kinase inhibitors | NOVARTIS AG | 2010-03-24 | — | — | CN | disclosed |