Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | KDM5C | P41229 | 5/20 | 0.46 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.46 |
| ▸ | KDM5A | P29375 | 2/20 | 0.46 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.46 |
| ▸ | KDM4B | O94953 | 2/20 | 0.45 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509023 | 0.85 | CYP1A2 (0.47) | CYP1A2POLBTSHRKDM4ELMNA | |
| SCHEMBL8594535 | 0.85 | CYP1A2 (0.47) | CYP1A2POLBTSHRKDM4ELMNA | |
| SCHEMBL30607268 | 0.85 | CYP1A2 (0.47) | CYP1A2POLBTSHRKDM4ELMNA | |
| SCHEMBL5566822 | 0.83 | CYP1A2 (0.46) | CYP1A2POLBTSHRKDM4ELMNA | |
| 2-Ethylisonicotinamide SCHEMBL2606610 | 0.83 | CYP1A2 (0.69) | CYP1A2POLBTSHRKDM4ELMNA | |
| SCHEMBL15991431 | 0.83 | CYP1A2 (0.46) | CYP1A2POLBTSHRKDM4ELMNA | |
| SCHEMBL7670706 | 0.82 | KDM4C (0.57) | KDM4EKDM5CKDM5BKDM4CKDM5A | |
| SCHEMBL5147899 | 0.81 | TSHR (0.51) | CYP1A2POLBTSHRKDM4ELMNA | |
| SCHEMBL17873933 | 0.80 | KDM4E (0.73) | CYP1A2POLBTSHRKDM4ELMNA | |
| SCHEMBL16115747 | 0.79 | KDM4E (0.49) | CYP1A2POLBTSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |