Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7215823 | 0.79 | ALDH1A1 (0.50) | CYP3A4MAPTTAAR1CYP1A2RIPK1 | |
| SCHEMBL5475632 | 0.73 | — | — | |
| SCHEMBL31118127 | 0.72 | SLC6A2 (0.47) | LMNACYP2D6CYP3A4ATMTAAR1 | |
| SCHEMBL17027416 | 0.70 | CYP1A2 (0.44) | LMNACYP2D6CYP3A4ATMTAAR1 | |
| SCHEMBL17027412 | 0.70 | CYP1A2 (0.44) | LMNACYP2D6CYP3A4ATMTAAR1 | |
| SCHEMBL9584084 | 0.70 | SLC6A2 (0.50) | LMNACYP2D6MAPTATMTAAR1 | |
| SCHEMBL24305738 | 0.69 | LMNA (0.61) | LMNACYP2D6KDM4ECYP3A4MAPT | |
| SCHEMBL10625675 | 0.69 | ATM (0.47) | LMNACYP2D6CYP3A4ATMTAAR1 | |
| SCHEMBL28558348 | 0.69 | SLC6A2 (0.52) | LMNACYP2D6KDM4ECYP3A4MAPT | |
| SCHEMBL5784144 | 0.69 | SLC6A2 (0.52) | LMNACYP2D6KDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101679433-A | Novel adenine compound | DAINIPPON SUMITOMO PHARMA CO | 2010-03-24 | — | — | CN | claimed |
| CN-101679433-A | Novel adenine compound | DAINIPPON SUMITOMO PHARMA CO | 2010-03-24 | — | — | CN | disclosed |