SCHEMBL27804166

SCHEMBL27804166

NC(=O)c1ncccc1S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
COMT P21964 1/20 0.44
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP1A2 P05177 2/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 5/20 0.40
MAPT P10636 3/20 0.40
BLM P54132 2/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
AGER Q15109 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
MAPK1 P28482 1/20 0.40
CA9 Q16790 1/20 0.40
PARP1 P09874 1/20 0.40
MKNK1 Q9BUB5 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8165111 0.85 CA1 (0.51) ALDH1A1ALOX15KDM4EMAPTBLM
SCHEMBL3914430 0.84 MKNK1 (0.41) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL12418385 0.83 KDM4E (0.55) COMTALDH1A1ALOX15HSD17B10CYP1A2
SCHEMBL27557525 0.81 P2RX7 (0.50) COMTALDH1A1ALOX15HSD17B10CYP1A2
SCHEMBL18940878 0.81 COMT (0.49) COMTALDH1A1ALOX15HSD17B10CYP1A2
SCHEMBL25296983 0.80 MEN1 (0.48) ALDH1A1ALOX15KDM4EMAPTBLM
SCHEMBL18960863 0.80 MKNK1 (0.39) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL17675152 0.80 SYK (0.38) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL27626910 0.78 TTR (0.51) COMTALDH1A1ALOX15HSD17B10CYP1A2
SCHEMBL12378236 0.77 L3MBTL1 (0.55) COMTALDH1A1ALOX15HSD17B10CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101990521-A Preparation of silver sulfate particles in the presence of a water-soluble fluorinated additive EASTMAN KODAK CO 2011-03-23 CN disclosed