Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27975311 | 0.77 | AKR1C3 (0.40) | GAAKDM4E | |
| SCHEMBL27660776 | 0.77 | NCF1 (0.41) | NCF1BRD4LMNAMC4RPNMT | |
| SCHEMBL28103283 | 0.73 | LGMN (0.31) | — | |
| SCHEMBL27947141 | 0.73 | LMNA (0.38) | LMNASMN1; SMN2 | |
| SCHEMBL27502833 | 0.67 | NCF1 (0.58) | NCF1BRD4MC4RPNMTKDM4E | |
| SCHEMBL27935635 | 0.67 | KDM4E (0.41) | LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL27583868 | 0.67 | MAPT (0.45) | THRBLMNAGAAGFERKDM4E | |
| SCHEMBL111193 | 0.66 | NCF1 (0.57) | NCF1BRD4LMNAGAASMN1; SMN2 | |
| SCHEMBL27834649 | 0.66 | NCF1 (0.71) | NCF1MC4RPNMTKDM4ESMN1; SMN2 | |
| SCHEMBL28753504 | 0.65 | NCF1 (0.55) | NCF1BRD4GAAGFERMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1989141-B | Bicyclic heterocycles as HIV integrase inhibitors | BRISTOL MYERS SQUIBB CO | 2010-06-16 | — | — | CN | disclosed |