Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.68 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.58 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL255989 | 0.87 | HDAC1 (0.77) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL23932950 | 0.85 | ALDH1A1 (0.67) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL231006 | 0.84 | NPC1 (0.63) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL27804582 | 0.83 | KDM4E (0.74) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL255987 | 0.81 | HDAC1 (0.68) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL174581 | 0.79 | HDAC1 (0.59) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL27929806 | 0.78 | ALDH1A1 (0.65) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL17318625 | 0.78 | NPC1 (0.63) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL255828 | 0.78 | ALDH1A1 (0.64) | HDAC1HDAC2MAPTALDH1A1RAB9A | |
| SCHEMBL8136410 | 0.78 | ALDH1A1 (0.55) | HDAC1HDAC2MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101723943-B | 1,3, 4-thiadiazolyl fluorouracil compounds and preparation method and application thereof | NANJING TECH UNIVERSITY (CN) | 2012-02-01 | — | — | CN | disclosed |
| CN-101723943-A | 1,3, 4-thiadiazolyl fluorouracil compounds and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2010-06-09 | — | — | CN | disclosed |