Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 17/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.54 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27804765 | 0.84 | MET (0.66) | METKCNH2 | |
| SCHEMBL27825389 | 0.79 | MET (0.55) | METKCNH2 | |
| SCHEMBL28790389 | 0.72 | MET (0.66) | METKCNH2 | |
| SCHEMBL27924860 | 0.72 | MET (1.00) | METKCNH2 | |
| SCHEMBL24962327 | 0.69 | IDO1 (0.52) | METIDO1TDO2 | |
| SCHEMBL2404063 | 0.69 | CA12 (0.69) | IDO1TDO2 | |
| SCHEMBL17491462 | 0.69 | PHGDH (0.53) | IDO1TDO2 | |
| Hydrochloric Acid SCHEMBL30101432 | 0.68 | IDO1 (0.51) | METIDO1TDO2 | |
| SCHEMBL27804767 | 0.68 | MET (0.61) | METKCNH2 | |
| SCHEMBL13923614 | 0.67 | LMNA (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101993416-B | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2013-09-11 | — | — | CN | disclosed |
| CN-101993416-A | Quinoline compound and preparation method thereof, medicament combination containing compound and application of compound | SHANGHAI INST MATERIA MEDICA | 2011-03-30 | — | — | CN | disclosed |