Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.39 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807046 | 0.83 | CHRM2 (0.44) | CHRM2CHRM4CHRM1CHRM3MTNR1A | |
| SCHEMBL28317897 | 0.75 | NOTUM (0.38) | CHRM2CHRM4CHRM1CHRM3AADAT | |
| SCHEMBL7554141 | 0.75 | NOTUM (0.49) | NOTUMALDH1A1 | |
| SCHEMBL4275949 | 0.75 | NOTUM (0.49) | NOTUMALDH1A1 | |
| SCHEMBL22064198 | 0.74 | CHRM2 (0.34) | CHRM2CHRM4CHRM1CHRM3NOTUM | |
| SCHEMBL28735654 | 0.71 | NOTUM (0.36) | AADATNOTUMGOT1KYAT1KYAT3 | |
| SCHEMBL27383076 | 0.71 | ACE (0.39) | NOTUM | |
| SCHEMBL27855041 | 0.70 | AADAT (0.37) | AADATNOTUMGOT1KYAT1KYAT3 | |
| SCHEMBL27585383 | 0.69 | MTNR1A (0.44) | CHRM2CHRM4CHRM1CHRM3KMT2A | |
| SCHEMBL30390623 | 0.68 | NOTUM (0.46) | NOTUMALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112159344-B | Synthesis method of 1, 3-dimethyl-3-hydroxymethyl indoline-2-ketone compound | 湖南科技学院 | 2021-11-09 | — | — | CN | disclosed |
| CN-112159344-A | Synthesis method of 1, 3-dimethyl-3-hydroxymethyl indoline-2-ketone compound | 湖南科技学院 | 2021-01-01 | — | — | CN | disclosed |