Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807931 | 0.98 | PIK3CA (0.43) | PIK3CAGABRG2GABRB3GABRA2BTK | |
| SCHEMBL27785957 | 0.96 | PIK3CA (0.39) | PIK3CAGABRG2GABRB3GABRA2BTK | |
| SCHEMBL27807909 | 0.90 | PDE1B (0.35) | PIK3CA | |
| SCHEMBL27786011 | 0.89 | BRD9 (0.36) | PIK3CAGABRG2GABRB3GABRA2 | |
| SCHEMBL27808006 | 0.88 | PIK3CA (0.37) | PIK3CAGABRG2GABRB3GABRA2BTK | |
| SCHEMBL27807913 | 0.87 | BRD9 (0.36) | PIK3CAGABRG2GABRB3GABRA2 | |
| SCHEMBL27786270 | 0.84 | GABRG2 (0.41) | GABRG2GABRB3GABRA2BTK | |
| SCHEMBL27785960 | 0.84 | PIK3CA (0.35) | PIK3CAGABRG2GABRB3GABRA2BTK | |
| SCHEMBL27807951 | 0.84 | GABRG2 (0.37) | PIK3CAGABRG2GABRB3GABRA2HRH4 | |
| SCHEMBL27785948 | 0.83 | GABRG2 (0.34) | PIK3CAGABRG2GABRB3GABRA2MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778849-A | Fused quinoline derivatives useful as gaba modulators | ASTRAZENECA AB | 2010-07-14 | — | — | CN | disclosed |