SCHEMBL27808201

SCHEMBL27808201

BrC1CCCC(c2ccsc2)C1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.32
ADORA2B P29275 2/20 0.32
CHRM2 P08172 1/20 0.30
CHRM4 P08173 1/20 0.30
CHRM5 P08912 1/20 0.30
CHRM1 P11229 1/20 0.30
CHRM3 P20309 1/20 0.30
KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3089324 0.82
SCHEMBL28686716 0.79 ADORA2B (0.34) HCAR2ADORA2BCHRM2CHRM4CHRM5
SCHEMBL18825946 0.78 KDR (0.41) HCAR2ADORA2BCHRM2CHRM4CHRM5
SCHEMBL31087550 0.77 KDR (0.43) HCAR2ADORA2BCHRM2CHRM4CHRM5
SCHEMBL146605 0.77 KDR (0.43) HCAR2ADORA2BCHRM2CHRM4CHRM5
SCHEMBL27607674 0.73 AKR1C3 (0.44)
Formic Acid SCHEMBL27498740 0.73 HCAR2 (0.38) HCAR2ADORA2BKDR
SCHEMBL28617553 0.70 ADORA2B (0.33) ADORA2B
SCHEMBL7764545 0.70 ESR2 (0.34)
SCHEMBL27320198 0.69 DRD2 (0.45) HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101945839-A Process for producing conjugated aromatic compound SUMITOMO CHEMICAL CO 2011-01-12 CN disclosed
CN-101827854-A Transition metal complex and method for producing conjugated aromatic compound using same SUMITOMO CHEMICAL CO 2010-09-08 CN disclosed
CN-101772508-A Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL CO 2010-07-07 CN disclosed