Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | METAP1 | P53582 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1025455 | 0.79 | NR4A2 (0.61) | NR4A2MAPK14KDM4EPDE4DMAPT | |
| SCHEMBL29291170 | 0.79 | CYP1A2 (0.56) | NR4A2MAPTLMNASMN1; SMN2ALOX12 | |
| SCHEMBL4011946 | 0.78 | NR4A2 (0.49) | NR4A2MAPK14KDM4EPDE4DMAPT | |
| SCHEMBL28021043 | 0.78 | NR4A2 (0.56) | NR4A2MAPK14KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL27809134 | 0.77 | NR4A2 (0.51) | NR4A2KDM4EPDE4DMAPTLMNA | |
| SCHEMBL4040116 | 0.75 | KDM4E (0.64) | KDM4EPDE4DMAPTLMNAHSP90AA1 | |
| SCHEMBL4016535 | 0.75 | PIK3CD (0.61) | NR4A2KDM4EPDE4DMAPTLMNA | |
| SCHEMBL27640890 | 0.74 | CCR1 (0.54) | KDM4EPDE4DMAPTLMNAHSP90AA1 | |
| SCHEMBL27278123 | 0.74 | NPC1 (0.57) | MAPK14KDM4EMAPTLMNASMN1; SMN2 | |
| SCHEMBL318769 | 0.73 | NR4A2 (0.68) | NR4A2MAPK14KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801925-A | antiviral compounds | GILEAD SCIENCES INC | 2010-08-11 | — | — | CN | disclosed |