Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | COMT | P21964 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | MMP14 | P50281 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28021043 | 0.85 | NR4A2 (0.56) | NR4A2NR1H2NR1H3KDM4ESMN1; SMN2 | |
| SCHEMBL4016535 | 0.84 | PIK3CD (0.61) | NR4A2NR1H2NR1H3MAPTKDM4E | |
| SCHEMBL4011946 | 0.81 | NR4A2 (0.49) | NR4A2NR1H2NR1H3MAPTKDM4E | |
| SCHEMBL31403405 | 0.81 | RPS6KA3 (0.48) | COMTMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7071518 | 0.79 | TOP2A (0.47) | COMTMAPTKDM4EMEN1KMT2A | |
| SCHEMBL6941422 | 0.78 | TOP2A (0.51) | COMTMEN1KMT2AALOX5PIK3CD | |
| SCHEMBL27809136 | 0.77 | NR4A2 (0.51) | NR4A2NR1H2NR1H3MAPTKDM4E | |
| SCHEMBL29291169 | 0.77 | CYP2A6 (0.54) | NR4A2MEN1KMT2AESR1USP7 | |
| SCHEMBL25521547 | 0.76 | NR1H2 (0.46) | NR4A2NR1H2NR1H3COMTMAPT | |
| SCHEMBL1025455 | 0.75 | NR4A2 (0.61) | NR4A2MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801925-A | antiviral compounds | GILEAD SCIENCES INC | 2010-08-11 | — | — | CN | disclosed |