Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27829555 | 0.89 | TSHR (0.62) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9776634 | 0.89 | TSHR (0.68) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12971050 | 0.89 | THRB (0.58) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17813263 | 0.87 | TSHR (0.42) | TSHRTHRBALDH1A1GLO1LMNA | |
| SCHEMBL11355650 | 0.84 | TSHR (0.61) | TSHRTHRBTDP1ALDH1A1HSD17B10 | |
| SCHEMBL10797778 | 0.84 | TSHR (0.65) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL27590660 | 0.84 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL22190966 | 0.84 | TSHR (0.59) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL1083624 | 0.83 | TSHR (0.75) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7983922 | 0.82 | ALDH1A1 (0.48) | TSHRTHRBALDH1A1GLO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101591428-B | Method for preparing dendritic macromolecule of polyester | UNIV ZHEJIANG | 2011-05-25 | — | — | CN | disclosed |