Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362652 | 0.86 | LMNA (0.52) | LMNACA5AALDH1A1HPGDMAPT | |
| SCHEMBL6678353 | 0.82 | CA5A (0.48) | LMNACA5AHPGDMAPTL3MBTL1 | |
| SCHEMBL1636309 | 0.79 | LMNA (0.46) | LMNACA5AALDH1A1HPGDGAA | |
| SCHEMBL6343891 | 0.72 | ALDH1A1 (0.61) | LMNACA5AALDH1A1HPGDABCB11 | |
| SCHEMBL1569458 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL744029 | 0.70 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2347540 | 0.68 | — | — | |
| SCHEMBL1816269 | 0.68 | CA1 (0.54) | LMNAALDH1A1HPGDGAAKDM4E | |
| SCHEMBL12526814 | 0.68 | LMNA (0.67) | LMNACA5AALDH1A1HPGDTPMT | |
| SCHEMBL221066 | 0.68 | ALDH1A1 (0.42) | LMNAALDH1A1HPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801925-A | antiviral compounds | GILEAD SCIENCES INC | 2010-08-11 | — | — | CN | disclosed |