Quinoline

Quinoline

SCHEMBL27809208

F[B-](F)(F)F.c1ccc2ncccc2c1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.81
NPC1 O15118 3/20 0.50
POLB P06746 1/20 0.50
RAB9A P51151 1/20 0.50
CYP3A4 P08684 3/20 0.48
HTT P42858 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPT P10636 3/20 0.47
CASP1 P29466 2/20 0.47
TP53 P04637 2/20 0.47
HSP90AA1 P07900 2/20 0.47
TSHR P16473 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 1/20 0.47
CASP7 P55210 1/20 0.47
KMT2A Q03164 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C19 P33261 1/20 0.47
NR4A2 P43354 1/20 0.47
HSP90AB1 P08238 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quinoline SCHEMBL27708937 0.98 ALDH1A1 (0.77) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28675260 0.94 ALDH1A1 (0.71) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL28937840 0.94 ALDH1A1 (0.71) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL1270969 0.90 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29349552 0.90 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL2774 0.90 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL29822171 0.90 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL32661377 0.90 ALDH1A1 (1.00) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL23202414 0.87 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4
Quinoline SCHEMBL5422407 0.87 ALDH1A1 (0.94) ALDH1A1NPC1POLBRAB9ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108350150-B Epoxy resin composition 亨斯迈先进材料许可(瑞士)有限公司 2021-09-10 CN disclosed
CN-108350150-A Composition epoxy resin 亨斯迈先进材料许可(瑞士)有限公司 2018-07-31 CN disclosed
CN-108290135-A Covalent organic frame with braiding structure 加利福尼亚大学董事会 2018-07-17 CN disclosed
CN-105121157-B Laminated body 综研化学株式会社 2017-08-08 CN disclosed
CN-101175830-B Adhesive composition, adhesive sheet, and surface protection film NITTO DENKO CORP 2011-05-25 CN disclosed