Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067071 | 0.86 | GPR35 (0.62) | GPR35ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL11075976 | 0.83 | GPR35 (0.59) | GPR35ALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL4132017 | 0.80 | GPR35 (0.69) | GPR35ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL8977819 | 0.80 | GPR35 (0.69) | GPR35ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL31392530 | 0.80 | GPR35 (0.69) | GPR35ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL322531 | 0.77 | GPR35 (1.00) | GPR35ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL11074065 | 0.76 | GPR35 (0.62) | GPR35ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL11065981 | 0.76 | GPR35 (0.62) | GPR35ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL11069356 | 0.76 | GPR35 (0.62) | GPR35ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL28817836 | 0.75 | GPR35 (0.95) | GPR35ALDH1A1MAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101786963-B | Synthesis method of Azasetron intermediate | SHANDONG Z C PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | claimed |
| CN-101786963-A | Synthesis method of Azasetron intermediate | SHANDONG ZHONGCHENG PHARMACEUT | 2010-07-28 | — | — | CN | claimed |
| CN-101786963-B | Synthesis method of Azasetron intermediate | SHANDONG Z C PHARMACEUTICAL CO LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-101786963-A | Synthesis method of Azasetron intermediate | SHANDONG ZHONGCHENG PHARMACEUT | 2010-07-28 | — | — | CN | disclosed |