Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GALR2 | O43603 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10877588 | 0.87 | GPR35 (0.55) | GPR35ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL6010756 | 0.85 | ALDH1A1 (0.51) | GPR35ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL2312711 | 0.85 | MAPT (0.54) | GPR35ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL5050015 | 0.85 | ALDH1A1 (0.53) | GPR35ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL11067071 | 0.84 | GPR35 (0.62) | GPR35ALDH1A1POLBHPGDMAPT | |
| SCHEMBL27809236 | 0.83 | GPR35 (0.61) | GPR35ALDH1A1POLBLMNAHPGD | |
| SCHEMBL27516180 | 0.83 | ALDH1A1 (0.49) | GPR35ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL7021997 | 0.83 | GPR35 (0.60) | GPR35ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL11074065 | 0.81 | GPR35 (0.62) | GPR35ALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL16529634 | 0.80 | ALDH1A1 (0.55) | ALDH1A1POLBLMNASMN1; SMN2GALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |