Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19207373 | 0.64 | TSHR (0.56) | ALDH1A1LMNATDP1CHRNB4CHRNA3 | |
| SCHEMBL19243529 | 0.64 | TSHR (0.56) | ALDH1A1LMNATDP1CHRNB4CHRNA3 | |
| SCHEMBL28845915 | 0.64 | ALDH1A1 (0.37) | SIRT2ALDH1A1SMN1; SMN2TDP1GAA | |
| SCHEMBL6938882 | 0.62 | CYP3A4 (0.44) | ALDH1A1SMN1; SMN2LMNATDP1POLB | |
| SCHEMBL12825154 | 0.61 | HSP90AA1 (0.57) | ALDH1A1LMNATDP1POLBAPEX1 | |
| SCHEMBL9304911 | 0.61 | SNCA (0.47) | SIRT2ALDH1A1SMN1; SMN2TDP1POLB | |
| SCHEMBL6327324 | 0.61 | HSP90AA1 (0.45) | LMNATDP1CHRNB4CHRNA3HSP90AA1 | |
| SCHEMBL6277445 | 0.61 | HSP90AA1 (0.45) | LMNATDP1CHRNB4CHRNA3HSP90AA1 | |
| SCHEMBL28092025 | 0.60 | CHRNB4 (0.67) | ALDH1A1LMNATDP1CHRNB4CHRNA3 | |
| SCHEMBL31220888 | 0.60 | TSHR (0.56) | ALDH1A1LMNATDP1CHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102070552-B | Preparation method of 3-amino-5-nitro-2, 1-benzisothiazole and diazonium salt thereof | Zhejiang jihua group co ltd | 2012-11-28 | — | — | CN | disclosed |
| CN-102070552-A | Preparation method of 3-amino-5-nitro-2, 1-benzisothiazole and diazonium salt thereof | Zhejiang jihua group co ltd | 2011-05-25 | — | — | CN | disclosed |