Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 4/20 | 0.47 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP4 | P49662 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP9 | P55211 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675185 | 0.83 | SNCA (0.48) | SNCACASP6CASP1CASP3CASP4 | |
| SCHEMBL8226386 | 0.72 | SNCA (0.78) | SNCACASP6CASP1CASP3CASP4 | |
| SCHEMBL5476176 | 0.71 | SNCA (0.40) | SNCACASP6CASP1CASP3CASP4 | |
| SCHEMBL28852929 | 0.71 | ALDH1A1 (0.44) | SNCACASP6CASP1CASP3CASP4 | |
| SCHEMBL27620706 | 0.71 | SNCA (0.42) | SNCACASP6CASP1CASP3CASP4 | |
| Iodide SCHEMBL11686704 | 0.70 | SNCA (0.41) | SNCACASP6CASP1CASP3CASP4 | |
| SCHEMBL30123443 | 0.69 | SNCA (0.49) | SNCACASP6CASP1CASP3CASP4 | |
| SCHEMBL30867072 | 0.68 | SNCA (0.70) | SNCACASP6CASP1CASP3CASP4 | |
| SCHEMBL29214118 | 0.68 | SNCA (0.70) | SNCACASP6CASP1CASP3CASP4 | |
| SCHEMBL6070223 | 0.68 | SNCA (0.48) | SNCACASP6CASP1CASP3CASP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5328993-A | Dyeing plastics; colorfastness, photostability | BAYER AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0567849-A1 | Process for preparing dyes | BAYER AG (DE) | 1993-11-03 | — | — | EP | disclosed |