SCHEMBL27809409

SCHEMBL27809409

O=S(=O)(Oc1nccs1)Oc1nccs1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
TSHR P16473 1/20 0.37
NOS1 P29475 1/20 0.37
HSD17B10 Q99714 1/20 0.37
SCN9A Q15858 1/20 0.36
FBP1 P09467 1/20 0.34
PDK1 Q15118 1/20 0.34
ACP1 P24666 2/20 0.34
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP2C9 P11712 1/20 0.33
EDNRA P25101 1/20 0.33
SLC6A4 P31645 1/20 0.33
ADRA1A P35348 1/20 0.33
PRMT6 Q96LA8 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TLR4 O00206 1/20 0.32
TLR2 O60603 1/20 0.32
PKM P14618 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28617469 0.85 ALDH1A1 (0.34) ALDH1A1TSHRNOS1HSD17B10SCN9A
SCHEMBL28170599 0.85 SCN9A (0.32) ALDH1A1TSHRNOS1HSD17B10SCN9A
SCHEMBL3165386 0.83 ALDH1A1 (0.39) ALDH1A1TSHRNOS1HSD17B10SCN9A
SCHEMBL5173136 0.83 ALDH1A1 (0.36) ALDH1A1TSHRNOS1HSD17B10SCN9A
SCHEMBL28170556 0.82 SCN9A (0.31) ALDH1A1SCN9AACP1
SCHEMBL2591217 0.81 ALDH1A1 (0.38) ALDH1A1TSHRNOS1HSD17B10SCN9A
SCHEMBL15510632 0.80 SCN9A (0.31) SCN9A
SCHEMBL27681940 0.79 CA12 (0.39) ALDH1A1TSHRNOS1HSD17B10FBP1
SCHEMBL30999657 0.75 METAP2 (0.45) ALDH1A1HSD17B10SCN9ALMNAKDM4E
SCHEMBL28372998 0.75 METAP2 (0.45) ALDH1A1HSD17B10SCN9ALMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101980643-B Temperature-stabilized medicinal storage systems TOKITAE LLC 2013-07-24 CN disclosed
CN-101980643-A Temperature-stabilized medicinal storage systems SEARETE LLC 2011-02-23 CN disclosed