Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2783032 | 0.91 | CXCR2 (0.47) | CXCR2ALDH1A1TRPV1KMT2ASMN1; SMN2 | |
| SCHEMBL2781727 | 0.80 | RARB (0.45) | ALDH1A1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL2784683 | 0.76 | FFAR1 (0.47) | ALDH1A1KMT2ASMN1; SMN2HDAC6MAPT | |
| SCHEMBL2130622 | 0.76 | CASR (0.52) | HRH3KMT2ASMN1; SMN2HDAC6MEN1 | |
| SCHEMBL2130616 | 0.76 | CASR (0.52) | HRH3KMT2ASMN1; SMN2HDAC6MEN1 | |
| SCHEMBL2781840 | 0.76 | TDP1 (0.41) | CNR2KMT2ASMN1; SMN2HPGDMEN1 | |
| SCHEMBL2780743 | 0.73 | TRPV1 (0.37) | TRPV1 | |
| SCHEMBL2779102 | 0.72 | MRGPRX4 (0.47) | ALDH1A1KMT2AHPGDMAPTKDM4E | |
| SCHEMBL2781623 | 0.70 | POLB (0.42) | HRH3ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL2781686 | 0.70 | CYP1A2 (0.48) | ALDH1A1KMT2ASMN1; SMN2HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | claimed |
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |