Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781727 | 0.88 | RARB (0.45) | L3MBTL1SLC16A3SIGMAR1KDM4ELMNA | |
| SCHEMBL2781686 | 0.86 | CYP1A2 (0.48) | L3MBTL1SIGMAR1KDM4ELMNACYP1A2 | |
| SCHEMBL2780803 | 0.83 | KAT8 (0.51) | L3MBTL1KDM4ELMNACYP1A2CYP2D6 | |
| SCHEMBL2781616 | 0.82 | LMNA (0.42) | L3MBTL1SIGMAR1KDM4ELMNACYP1A2 | |
| SCHEMBL2784683 | 0.81 | FFAR1 (0.47) | L3MBTL1SIGMAR1KDM4ELMNACYP1A2 | |
| Hydrochloric Acid SCHEMBL2779523 | 0.80 | SLC16A3 (0.49) | L3MBTL1SLC16A3SIGMAR1KDM4ELMNA | |
| SCHEMBL2782718 | 0.78 | CYP1A2 (0.47) | KDM4ECYP1A2CYP2D6CYP2C19PPARG | |
| SCHEMBL3955369 | 0.77 | KDM4E (0.47) | MRGPRX4L3MBTL1SIGMAR1KDM4ELMNA | |
| SCHEMBL10995885 | 0.77 | L3MBTL1 (0.52) | L3MBTL1SIGMAR1KDM4ELMNAMEN1 | |
| SCHEMBL2783032 | 0.76 | CXCR2 (0.47) | L3MBTL1SIGMAR1KDM4ELMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | claimed |
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |