Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 1/20 | 0.40 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | PPIG | Q13427 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27611924 | 0.88 | KDM4E (0.39) | ALDH1A1MAPK1L3MBTL1MEN1MAPT | |
| SCHEMBL27630941 | 0.88 | TPSAB1 (0.44) | ALDH1A1MAPK1L3MBTL1MEN1MAPT | |
| SCHEMBL6453211 | 0.87 | ALDH1A1 (0.47) | PPIBPPIAPPIDPPIGALDH1A1 | |
| SCHEMBL27611950 | 0.86 | MEN1 (0.42) | ALDH1A1MAPK1L3MBTL1MEN1MAPT | |
| SCHEMBL11736357 | 0.83 | PPIB (0.44) | PPIBPPIAPPIDPPIGALDH1A1 | |
| SCHEMBL2780510 | 0.82 | ALDH1A1 (0.42) | ALDH1A1MAPK1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL27611926 | 0.82 | TSHR (0.43) | ALDH1A1L3MBTL1TSHRSMN1; SMN2TDP1 | |
| SCHEMBL19439087 | 0.82 | PPID (0.57) | PPIBPPIAPPIDPPIGALDH1A1 | |
| SCHEMBL8526941 | 0.81 | PPID (0.39) | PPIBPPIAPPIDPPIGALDH1A1 | |
| SCHEMBL2778041 | 0.78 | CA1 (0.40) | ALDH1A1MAPK1L3MBTL1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2248901-A1 | Streptogramines and method for preparing same by mutasynthesis | Aventis Pharma S.A. (FR) | 2010-11-10 | — | — | EP | disclosed |
| EP-0770132-B1 | NEW STREPTOGRAMINES | AVENTIS PHARMA SA (FR) | 2010-09-08 | — | — | EP | disclosed |
| EP-0770132-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | Aventis Pharma S.A. (FR) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001901-A1 | STREPTOGRAMINES AND METHOD FOR PREPARING SAME BY MUTASYNTHESIS | RHONE-POULENC RORER S.A. (FR) | 1996-01-25 | — | — | WO | disclosed |