Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.43 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926203 | 0.80 | KDM4E (0.49) | KDM4EMAPK10ALDH1A1RAB9ALMNA | |
| SCHEMBL22819499 | 0.74 | MAP2K4 (0.66) | MAP2K4KDM4EMAPK10ALDH1A1IDO1 | |
| SCHEMBL27305897 | 0.74 | ELANE (0.52) | KDM4EALDH1A1GAARAB9ASMN1; SMN2 | |
| Tert-Butyl Formate SCHEMBL27811453 | 0.74 | MAP2K4 (0.51) | MAP2K4KDM4EMAPK10ALDH1A1IDO1 | |
| SCHEMBL4488472 | 0.73 | KDM4E (0.74) | MAP2K4KDM4EMAPK10ALDH1A1IDO1 | |
| SCHEMBL11903949 | 0.73 | MAP2K4 (0.63) | MAP2K4KDM4EMAPK10ALDH1A1IDO1 | |
| SCHEMBL522510 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HPGDRAB9ALMNASMN1; SMN2 | |
| SCHEMBL4200287 | 0.71 | IDO1 (0.71) | MAP2K4KDM4EMAPK10ALDH1A1IDO1 | |
| Ammonia Solution, Strong SCHEMBL27451848 | 0.71 | ALDH1A1 (0.60) | ALDH1A1HPGDRAB9ALMNASMN1; SMN2 | |
| SCHEMBL28246707 | 0.71 | ALDH1A1 (0.60) | ALDH1A1HPGDRAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102089302-A | Nitrogenated bicyclic heterocyclic compound | ASAHI KASEI PHARMA CORP | 2011-06-08 | — | — | CN | disclosed |