Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811592 | 0.65 | KDM4E (0.38) | ADORA2AADORA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28787791 | 0.59 | KCNH2 (0.32) | — | |
| SCHEMBL20377491 | 0.59 | — | — | |
| SCHEMBL12495474 | 0.57 | SMN1; SMN2 (0.46) | ADORA2AADORA1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL25423635 | 0.57 | — | — | |
| SCHEMBL13440864 | 0.57 | — | — | |
| SCHEMBL17863738 | 0.57 | — | — | |
| SCHEMBL29951802 | 0.56 | SMN1; SMN2 (0.40) | KDM4EHPGDSMN1; SMN2RAB9A | |
| SCHEMBL13255976 | 0.56 | RAB9A (0.35) | KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL1078235 | 0.56 | L3MBTL1 (0.37) | ADORA2AADORA1KDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102098918-A | Bioactive compounds for treatment of cancer and neurodegenerative diseases | PONIARD PHARMACEUTICALS INC | 2011-06-15 | — | — | CN | disclosed |