Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPN | P05981 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27814220 | 0.86 | ALDH1A1 (0.51) | ALDH1A1FGFR1MAPTMEN1KMT2A | |
| SCHEMBL27793073 | 0.85 | SCN2A (0.49) | POLBALDH1A1SCN2AMAPTMEN1 | |
| SCHEMBL27792987 | 0.78 | NPC1 (0.43) | POLBALDH1A1SCN2AFGFR1MAPT | |
| SCHEMBL27793176 | 0.78 | ALDH1A1 (0.42) | ALDH1A1SCN2AFGFR1MAPTKMT2A | |
| SCHEMBL27814208 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AHTT | |
| SCHEMBL28287781 | 0.74 | ALDH1A1 (0.64) | POLBALDH1A1SCN2AFGFR1MAPT | |
| SCHEMBL6367092 | 0.73 | TDP1 (0.50) | ALDH1A1MEN1KMT2AHTTNPC1 | |
| SCHEMBL27792940 | 0.73 | S100A4 (0.42) | POLBALDH1A1FGFR1MAPTMEN1 | |
| SCHEMBL27793005 | 0.73 | MAPT (0.46) | POLBALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL27793080 | 0.73 | ALDH1A1 (0.51) | POLBALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101817774-B | Method for preparing 2-(2-nitrophenyl) pyrrole and 2,5-bis(2-nitrophenyl) pyrrole compounds | YUEFEI HU | 2012-03-21 | — | — | CN | disclosed |
| CN-101817774-A | Method for preparing 2-(2-nitrophenyl) pyrrole and 2,5-bis(2-nitrophenyl) pyrrole compounds | YUEFEI HU | 2010-09-01 | — | — | CN | disclosed |