Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL934710 | 0.86 | EPHX1 (0.44) | EPHX1KDM4AKDM5ANOTUMTRPV1 | |
| SCHEMBL8225538 | 0.83 | PGK1 (0.46) | EPHX1KDM4AKDM5ANOTUMTRPV1 | |
| SCHEMBL27962418 | 0.81 | KCNH2 (0.43) | KCNN4KCNH2TMEM97SIGMAR1 | |
| SCHEMBL9824390 | 0.81 | EPHX1 (0.45) | EPHX1KDM4AKDM5ANOTUMTRPV1 | |
| SCHEMBL8185415 | 0.79 | EPHX1 (0.44) | EPHX1KDM4AKDM5ANOTUMTRPV1 | |
| SCHEMBL4374816 | 0.79 | CSNK2A1 (0.47) | EPHX1KDM4AKDM5ANOTUMKCNN4 | |
| SCHEMBL30176060 | 0.79 | CSNK2A1 (0.47) | EPHX1KDM4AKDM5ANOTUMKCNN4 | |
| SCHEMBL2240142 | 0.79 | NOTUM (0.51) | EPHX1KDM4AKDM5ANOTUMTRPV1 | |
| SCHEMBL3754799 | 0.79 | EPHX1 (0.44) | EPHX1KDM4AKDM5ANOTUMTRPV1 | |
| SCHEMBL8926703 | 0.78 | EPHX2 (0.44) | KCNH2TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801972-A | Pyrazolo [1,5-A]pyrimidines as inhibitors of stearoyl-coA desaturase | INOVACIA AB | 2010-08-11 | — | — | CN | disclosed |