Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.52 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.52 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17749049 | 0.78 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL11726006 | 0.78 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL6819115 | 0.78 | CHRM2 (0.48) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL34663 | 0.76 | CHRM2 (0.42) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL9031379 | 0.72 | CHRM2 (0.59) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL5005449 | 0.72 | HTR1A (0.41) | CHRM2CHRM3MEN1KMT2APOLB | |
| SCHEMBL8863095 | 0.71 | POLB (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL8862946 | 0.71 | CHRM2 (0.41) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL2639486 | 0.71 | MGLL (0.50) | ALDH1A1RAB9ASMN1; SMN2FAAHMGLL | |
| SCHEMBL11724860 | 0.69 | CHRM2 (1.00) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105026432-A | Aprotinin-derived polypeptide-antibody conjugates | ANGIOCHEM INC | 2015-11-04 | — | — | CN | claimed |
| CN-104781281-A | Conjugates including an antibody moiety, a polypeptide that traverses the blood-brain barrier, and a cytotoxin | ANGIOCHEM INC | 2015-07-15 | — | — | CN | claimed |
| EP-0941738-B1 | Antigenic conjugates of conserved lipooligosaccharides of gram negative bacteria | WYETH CORP (US) | 2005-05-11 | — | — | EP | claimed |
| US-20040052804-A1 | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria | WYETH HOLDINGS CORPORATION | 2004-03-18 | — | — | US | claimed |
| US-6645503-B1 | Eliciting a cross reactive immune response against heterologous strains of the gram negative bacteria; vaccines; comprises the inner core and lipid A portions of the lipopolysaccharide | WYETH HOLDINGS CORPORATION | 2003-11-11 | — | — | US | claimed |
| EP-0941738-A1 | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria | American Cyanamid Company (US) | 1999-09-15 | — | — | EP | claimed |
| EP-3935385-A1 | METHODS FOR DETECTING AND QUANTIFYING MEMBRANE-ASSOCIATED PROTEINS ON EXTRACELLULAR VESICLES | F. Hoffmann-La Roche AG (CH) | 2022-01-12 | — | — | EP | disclosed |
| WO-2020185535-A1 | METHODS FOR DETECTING AND QUANTIFYING MEMBRANE-ASSOCIATED PROTEINS ON EXTRACELLULAR VESICLES | GENENTECH, INC. (US) | 2020-09-17 | — | — | WO | disclosed |
| CN-110461354-A | Protein conjugate | TDW GROUP | 2019-11-15 | — | — | CN | disclosed |
| CN-109071670-A | Antibody and antibody fragment for locus specificity conjugation | 辉瑞公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108135929-A | System and method for continuous health monitoring using photo-enzymatic analyte sensors | 梅特罗诺姆保健公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-103747807-B | P97-antibody conjugates and methods of use | 比奥阿赛斯技术有限公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-106110332-A | Protein polymer drug conjugate | 梅尔莎纳医疗公司 | 2016-11-16 | — | — | CN | disclosed |
| US-4416817-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-11-22 | — | — | US | disclosed |
| EP-0021676-B1 | 3-METHOXY-2-OXOAZETIDINE DERIVATIVES AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1983-09-14 | — | — | EP | disclosed |
| EP-0053815-A1 | 2-Oxoazetidine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-16 | — | — | EP | disclosed |
| EP-0053387-A1 | Method of preparing 1-sulfo-2-oxoazetidine derivatives and intermediates therefor | Takeda Chemical Industries, Ltd. (JP) | 1982-06-09 | — | — | EP | disclosed |
| EP-0050965-A1 | Beta-lactamase inhibitory composition | Takeda Chemical Industries, Ltd. (JP) | 1982-05-05 | — | — | EP | disclosed |
| EP-0021676-A1 | 3-Methoxy-2-oxoazetidine derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040052804-A1 | Antigenic conjugates of conserved lipopolysaccharides of gram negative bacteria | LY96, DDOST, LRBA | CHRM2 4853/4885CHRM4 4768/4885CHRM5 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.