Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765292 | 0.86 | CA1 (0.45) | MAPTTMPRSS6ALDH1A1KDM4EKMT2A | |
| SCHEMBL7500671 | 0.77 | KMT2A (0.46) | MAPTALDH1A1KDM4EKMT2ACA1 | |
| Water SCHEMBL27768309 | 0.75 | KMT2A (0.44) | MAPTALDH1A1KDM4EKMT2ACA1 | |
| SCHEMBL11798964 | 0.74 | CA1 (0.43) | MAPTALDH1A1KDM4EKMT2ACA1 | |
| Biguanide SCHEMBL27815665 | 0.73 | TSHR (0.64) | TMPRSS6ALDH1A1KDM4ECA1CA2 | |
| SCHEMBL11238098 | 0.72 | SMN1; SMN2 (0.44) | MAPTTMPRSS6ALDH1A1KDM4EKMT2A | |
| SCHEMBL28081700 | 0.72 | BCAT1 (0.50) | ALDH1A1KMT2ACA1CA2MMP1 | |
| SCHEMBL11665830 | 0.70 | MAPT (0.40) | MAPTTMPRSS6ALDH1A1KDM4EKMT2A | |
| SCHEMBL27752562 | 0.70 | MAPT (0.54) | MAPTALDH1A1KMT2ACA1CA2 | |
| SCHEMBL5026989 | 0.70 | CA1 (0.46) | MAPTALDH1A1KDM4EKMT2ACA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101862315-A | Application of disubstituted phenyl biguanide to inducing malignant tumor cell for anoikis | INST OF HEMATOLOGY & BLOOD DISEASES HOSPITAL CHINESE ACADEMY OF MEDICAL SCIENCES | 2010-10-20 | — | — | CN | claimed |
| CN-108471750-B | Composition for pest control containing iminopyridine derivative | 明治制果药业株式会社 | 2020-11-20 | — | — | CN | disclosed |
| CN-101862315-A | Application of disubstituted phenyl biguanide to inducing malignant tumor cell for anoikis | INST OF HEMATOLOGY & BLOOD DISEASES HOSPITAL CHINESE ACADEMY OF MEDICAL SCIENCES | 2010-10-20 | — | — | CN | disclosed |