Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815664 | 0.86 | MAPT (0.37) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL7500671 | 0.82 | KMT2A (0.46) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3179301 | 0.81 | F2 (0.49) | CA1CA2MMP1MMP2MMP9 | |
| Water SCHEMBL27768309 | 0.81 | KMT2A (0.44) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11798964 | 0.80 | CA1 (0.43) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11238098 | 0.78 | SMN1; SMN2 (0.44) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28081700 | 0.77 | BCAT1 (0.50) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1269819 | 0.76 | CA2 (0.54) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11665830 | 0.76 | MAPT (0.40) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL27752562 | 0.76 | MAPT (0.54) | CA1CA2MAPTCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206334-B | Process for preparing aminopyrimidine compounds | 艾库斯生物科学有限公司 | 2025-01-07 | — | — | CN | claimed |
| EP-3980013-B1 | PROCESSES FOR PREPARING AMINOPYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES INC (US) | 2024-07-31 | — | — | EP | claimed |
| US-20220235031-A1 | PROCESSES FOR PREPARING AMINOPYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES, INC. | 2022-07-28 | — | — | US | claimed |
| CN-114206334-A | Process for preparing aminopyrimidine compounds | 艾库斯生物科学有限公司 | 2022-03-18 | — | — | CN | claimed |
| WO-2020247789-A1 | PROCESSES FOR PREPARING AMINOPYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES, INC. (US) | 2020-12-10 | — | — | WO | claimed |
| US-12630526-B2 | Processes for preparing aminopyrimidine compounds | ARCUS BIOSCIENCES, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| CN-114206334-B | Process for preparing aminopyrimidine compounds | 艾库斯生物科学有限公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3980013-B1 | PROCESSES FOR PREPARING AMINOPYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES INC (US) | 2024-07-31 | — | — | EP | disclosed |
| US-20220235031-A1 | PROCESSES FOR PREPARING AMINOPYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES, INC. | 2022-07-28 | — | — | US | disclosed |
| CN-114206334-A | Process for preparing aminopyrimidine compounds | 艾库斯生物科学有限公司 | 2022-03-18 | — | — | CN | disclosed |
| WO-2020247789-A1 | PROCESSES FOR PREPARING AMINOPYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES, INC. (US) | 2020-12-10 | — | — | WO | disclosed |
| CN-1491939-A | Hexa alkyl guanidine salt ion liquid and preparing process | 中国科学院长春应用化学研究所 | 2004-04-28 | — | — | CN | disclosed |
| EP-0890355-B1 | Hair treatment composition | KAO CORP (JP) | 2001-05-30 | — | — | EP | disclosed |
| US-6071504-A | GUANIDIUM SALT, AMINO-MODIFIED POLYSILOXANE; ODORLESS, SKIN SENSITIVITY | KAO CORPORATION (JP) | 2000-06-06 | — | — | US | disclosed |
| EP-0890355-A1 | Hair treatment composition | Kao Corporation (JP) | 1999-01-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12630526-B2 | Processes for preparing aminopyrimidine compounds | PAICS, CCNL2, UCK2 | CA1 1536/4885CA2 1044/4885MMP1 4848/4885 |
| US-20220235031-A1 | PROCESSES FOR PREPARING AMINOPYRIMIDINE COMPOUNDS | DPYD, TYMP, DHPS | CA1 4424/4885CA2 4769/4885MMP1 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.