Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27816056 | 0.84 | CACNA1H (0.41) | KMT2AMEN1NPC1RAB9AAADAT | |
| SCHEMBL28788395 | 0.76 | NPBWR1 (0.44) | CMA1 | |
| SCHEMBL29339779 | 0.74 | CYP1A2 (0.46) | KMT2AMEN1NPC1RAB9AAADAT | |
| SCHEMBL4552450 | 0.74 | MEN1 (0.45) | KMT2AMEN1NPC1RAB9APTGS2 | |
| SCHEMBL29339884 | 0.74 | KMT2A (0.37) | KMT2AMEN1NPC1RAB9AAADAT | |
| SCHEMBL3357203 | 0.74 | GSK3B (0.44) | KMT2AMEN1NPC1RAB9AAADAT | |
| SCHEMBL29339707 | 0.73 | MEN1 (0.44) | KMT2AMEN1NPC1RAB9APTGS2 | |
| SCHEMBL3359322 | 0.73 | KMT2A (0.46) | KMT2AMEN1NPC1RAB9AAADAT | |
| SCHEMBL370507 | 0.72 | KMT2A (0.53) | KMT2AMEN1NPC1RAB9AAADAT | |
| SCHEMBL29340025 | 0.71 | AADAT (0.34) | KMT2AMEN1NPC1RAB9AAADAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101874029-A | Pyrazole derivatives as metabotropic glutamate receptor modulators | ADDEX PHARMACEUTICALS SA | 2010-10-27 | — | — | CN | disclosed |