SCHEMBL277760

SCHEMBL277760

Cln1cnc2ccccc21

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.54
SMN1; SMN2 Q16637 4/20 0.53
LMNA P02545 3/20 0.53
STAT6 P42226 1/20 0.53
HTT P42858 4/20 0.52
CYP11B1 P15538 4/20 0.52
CYP11B2 P19099 4/20 0.52
TNF P01375 1/20 0.52
MAPK1 P28482 1/20 0.47
POLB P06746 1/20 0.47
FGFR1 P11362 2/20 0.46
MEN1 O00255 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
HSD17B10 Q99714 1/20 0.44
ALDH3A1 P30838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7196401 0.75 TDP1 (0.58) TDP1SMN1; SMN2LMNASTAT6HTT
SCHEMBL2489876 0.73 TDP1 (0.56) TDP1SMN1; SMN2LMNASTAT6HTT
SCHEMBL145442 0.71 TDP1 (0.54) TDP1SMN1; SMN2LMNASTAT6HTT
SCHEMBL460599 0.71 TDP1 (0.54) TDP1SMN1; SMN2LMNASTAT6HTT
SCHEMBL39078 0.71 TDP1 (0.54) TDP1SMN1; SMN2LMNASTAT6HTT
SCHEMBL9062626 0.71 TDP1 (0.54) TDP1SMN1; SMN2LMNASTAT6HTT
SCHEMBL5399 0.71 TDP1 (0.59) TDP1SMN1; SMN2LMNAHTTCYP11B1
SCHEMBL8668369 0.71 TDP1 (0.54) TDP1SMN1; SMN2LMNASTAT6HTT
SCHEMBL278161 0.71 TDP1 (0.54) TDP1SMN1; SMN2LMNASTAT6HTT
SCHEMBL222667 0.71 TDP1 (0.54) TDP1SMN1; SMN2LMNASTAT6HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12263464-B2 Method for in-situ synthesis of metal organic frameworks (MOFs), covalent organic frameworks (COFs) and zeolite imidazolate frameworks (ZIFs), and applications thereof DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2025-04-01 US claimed
WO-2023202368-A1 NUCLEIC ACID ENCAPSULATION AND DECAPSULATION METHOD AND NUCLEIC ACID STORAGE MICRO-FLUIDIC CHIP 南方科技大学 2023-10-26 WO claimed
CN-219239914-U Anti-mite antibacterial deodorant moisture-conducting knitted fabric 江苏品创纺织科技有限公司 2023-06-23 CN claimed
EP-3801880-A1 METHOD FOR IN-SITU SYNTHESIS OF METAL ORGANIC FRAMEWORKS (MOFS), COVALENT ORGANIC FRAMEWORKS (COFS) AND ZEOLITE IMIDAZOLATE FRAMEWORKS (ZIFS), AND APPLICATIONS THEREOF Desiccant Rotors International Private Ltd. (IN) 2021-04-14 EP claimed
US-20210016245-A1 METHOD FOR IN-SITU SYNTHESIS OF METAL ORGANIC FRAMEWORKS (MOFs), COVALENT ORGANIC FRAMEWORKS (COFs) AND ZEOLITE IMIDAZOLATE FRAMEWORKS (ZIFs), AND APPLICATIONS THEREOF DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2021-01-21 US claimed
EP-1564212-B1 PROCESS AND INTERMEDIATES FOR OBTAINING 1-(1H-BENZIMIDAZOL-2-YL)-4-(PYRIMIDIN-2-YLAMINO)PIPERIDINE DERIVATIVES RAGACTIVES SL (ES) 2007-12-12 EP claimed
US-20050228006-A1 Process and intermediates for obtaining 1-(1H-benzimidazol-2-YL)-4-(2-aminopyrimidine)piperidine derivatives RAGACTIVES, S.L. 2005-10-13 US claimed
EP-1564212-A1 METHOD AND INTERMEDIA USED TO OBTAIN DERIVATIVES OF 1-(1H- BENZIMIDAZOLE-2-YL)-4-(2-AMINOPYRIMIDINE)PIPERIDINE Ragactives, S.L. (ES) 2005-08-17 EP claimed
US-12492185-B2 Benzimidazole derivatives and their uses TEIJIN PHARMA LIMITED (JP) 2025-12-09 US disclosed
US-20250249431-A1 METAL-ORGANIC FRAMEWORK FILM AND METHOD FOR PRODUCING SAME MURATA MANUFACTURING CO., LTD. (JP) 2025-08-07 US disclosed
EP-3952866-B1 BENZIMIDAZOLE DERIVATIVES AND THEIR USES TEIJIN PHARMA LTD (JP) 2025-07-23 EP disclosed
CN-120018905-A Metal organic structure film and method for producing same 株式会社村田制作所 2025-05-16 CN disclosed
CN-113424016-B Method for obtaining information on an organic solderability preservative on a printed circuit board 德国艾托特克公司 2025-04-15 CN disclosed
US-12263464-B2 Method for in-situ synthesis of metal organic frameworks (MOFs), covalent organic frameworks (COFs) and zeolite imidazolate frameworks (ZIFs), and applications thereof DESICCANT ROTORS INTERNATIONAL PRIVATE LIMITED (IN) 2025-04-01 US disclosed
US-4266018-A SUBSTITUTED THIOUREA SENSITIZERS FUJI PHOTO FILM CO., LTD. (JP) 1981-05-05 US disclosed
US-4243739-A HYDRAZIDE FUJI PHOTO FILM CO., LTD. (JP) 1981-01-06 US disclosed
US-4198240-A SENSITIZERS COMPRISING THIOETHER AND THIOSULFONE COMPOUNDS FUJI PHOTO FILM CO., LTD. (JP) 1980-04-15 US disclosed
US-4152163-A Silver halide photographic emulsion containing cyanine and hemicyanine sensitizing dyes FUJI PHOTO FILM CO., LTD. (JP) 1979-05-01 US disclosed
US-4110115-A SILVER HALIDE, MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1978-08-29 US disclosed
US-4040840-A MEROCYANINE DYE HAVING ISOXAZOLE NUCLEUS AND PYRAZOLINE-5-ONE NUCLEUSN FUJI PHOTO FILM CO., LTD. (JA) 1977-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12492185-B2 Benzimidazole derivatives and their uses TRPC6, TRPC4, TRPC3 TDP1 2023/4885SMN1; SMN2 3718/4885LMNA 2375/4885
US-20050228006-A1 Process and intermediates for obtaining 1-(1H-benzimidazol-2-YL)-4-(2-aminopyrimidine)piperidine derivatives IL2, IL4, IL4I1 TDP1 4142/4885SMN1; SMN2 3736/4885LMNA 3312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.