Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780803 | 0.88 | KAT8 (0.51) | LMNACYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL2782718 | 0.82 | CYP1A2 (0.47) | CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL2779102 | 0.82 | MRGPRX4 (0.47) | LMNACYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL2781727 | 0.82 | RARB (0.45) | LMNACYP1A2CYP2D6L3MBTL1KDM4E | |
| SCHEMBL2780500 | 0.81 | KDM4E (0.44) | CYP1A2CYP2D6CYP2C19KDM4EALDH1A1 | |
| SCHEMBL2781686 | 0.80 | CYP1A2 (0.48) | LMNACYP1A2CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL2784683 | 0.80 | FFAR1 (0.47) | LMNACYP1A2CYP2D6CYP2C19L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2779523 | 0.79 | SLC16A3 (0.49) | LMNAL3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL2783032 | 0.73 | CXCR2 (0.47) | LMNACYP1A2CYP2D6L3MBTL1KDM4E | |
| SCHEMBL2130735 | 0.72 | CASR (0.60) | CYP2D6HTTSIGMAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | claimed |
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |