Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2781686 | 0.86 | CYP1A2 (0.48) | CYP1A2CYP2D6CYP2C19FFAR1AKR1B1 | |
| SCHEMBL2784683 | 0.86 | FFAR1 (0.47) | CYP1A2CYP2D6CYP2C19FFAR1AKR1B1 | |
| SCHEMBL2781616 | 0.82 | LMNA (0.42) | CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL2780500 | 0.82 | KDM4E (0.44) | CYP1A2CYP2D6CYP2C19FFAR1KDM4E | |
| SCHEMBL2779102 | 0.78 | MRGPRX4 (0.47) | CYP1A2CYP2D6CYP2C19KDM4EPPARG | |
| SCHEMBL2781727 | 0.77 | RARB (0.45) | CYP1A2CYP2D6KDM4E | |
| SCHEMBL2780803 | 0.77 | KAT8 (0.51) | CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL2782301 | 0.76 | POLB (0.44) | FFAR1FFAR4RXRGRXRARXRB | |
| SCHEMBL2132416 | 0.73 | CASR (0.57) | CYP1A2CYP2D6CYP2C19FFAR1FFAR4 | |
| SCHEMBL2132422 | 0.73 | CASR (0.57) | CYP1A2CYP2D6CYP2C19FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | claimed |
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |