Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27824038 | 0.88 | ALOX5 (0.49) | ALOX5HCRTR1HCRTR2LMNAKDM4E | |
| SCHEMBL27824189 | 0.87 | ALOX5 (0.64) | ALOX5HCRTR1HCRTR2KDM4EMAPT | |
| SCHEMBL27803408 | 0.85 | ALOX5 (0.47) | ALOX5HCRTR1HCRTR2KDM4EALDH1A1 | |
| SCHEMBL27824196 | 0.84 | SLC6A3 (0.44) | ALOX5HCRTR1HCRTR2MAPTSLC6A3 | |
| SCHEMBL27817791 | 0.80 | ALOX5 (0.37) | ALOX5HCRTR1HCRTR2KDM4EHPGD | |
| SCHEMBL27824198 | 0.80 | ALOX5 (0.43) | ALOX5HCRTR1HCRTR2LMNAMAPT | |
| SCHEMBL27803414 | 0.80 | ALOX5 (0.54) | ALOX5MAPK14KDM4EHPGDPTGS1 | |
| SCHEMBL28786380 | 0.80 | ALOX5 (0.54) | ALOX5HCRTR1HCRTR2MAPK14PTGS1 | |
| SCHEMBL27803545 | 0.79 | ALOX5 (0.52) | ALOX5LMNAMAPK14KDM4EMAPT | |
| SCHEMBL27818021 | 0.78 | ALOX5 (0.44) | ALOX5MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |