Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14632053 | 0.87 | FBP1 (0.44) | ALOX5FBP1KDM4EPKMALDH1A1 | |
| SCHEMBL27817803 | 0.87 | KDM4E (0.54) | ALOX5FBP1KDM4EPKMALDH1A1 | |
| SCHEMBL27626587 | 0.85 | ALOX5 (0.71) | ALOX5KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL27803414 | 0.84 | ALOX5 (0.54) | ALOX5KDM4EPKMALDH1A1HPGD | |
| SCHEMBL28786380 | 0.84 | ALOX5 (0.54) | ALOX5PKMALDH1A1GRM6MAPK14 | |
| SCHEMBL27824237 | 0.84 | ALOX5 (0.51) | ALOX5KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL27817817 | 0.81 | ALDH1A1 (0.49) | ALOX5KDM4EPKMALDH1A1SMN1; SMN2 | |
| SCHEMBL27817836 | 0.79 | ALOX5 (0.48) | ALOX5KDM4EPKMALDH1A1HPGD | |
| SCHEMBL28790352 | 0.78 | ALOX5 (0.47) | ALOX5FBP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL27803421 | 0.76 | ALOX5 (0.51) | ALOX5KDM4EPKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
| CN-101965343-A | 2-aza-bicyclo[2.2.1]heptane derivatives | ACTELION PHARMACEUTICALS LTD | 2011-02-02 | — | — | CN | disclosed |