Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044362 | 0.77 | GPR3 (0.46) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL17456836 | 0.75 | GPR3 (0.44) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL6502792 | 0.73 | KMT2A (0.47) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL27549930 | 0.73 | GPR3 (0.42) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL4600049 | 0.72 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL4603276 | 0.72 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL30510269 | 0.72 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL1830100 | 0.72 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL30510362 | 0.72 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL31355068 | 0.72 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101932592-B | Antitumoral compounds | PHARMA MAR SA | 2014-02-26 | — | — | CN | disclosed |
| CN-103038240-A | Synthetic method for preparing ecteinascidin compounds | PHARMA MAR SA | 2013-04-10 | — | — | CN | disclosed |
| CN-101932592-A | Antineoplastic compound | PHARMA MAR SA | 2010-12-29 | — | — | CN | disclosed |