Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503351 | 0.81 | KMT2A (0.54) | KMT2AGAAGPR3MEN1LMNA | |
| SCHEMBL21925560 | 0.77 | MAPT (0.41) | KMT2AGPR3MEN1LMNAPOLB | |
| SCHEMBL3044362 | 0.76 | GPR3 (0.46) | KMT2AGAAGPR3MEN1LMNA | |
| SCHEMBL17456836 | 0.74 | GPR3 (0.44) | KMT2AGAAGPR3MEN1LMNA | |
| SCHEMBL27819079 | 0.73 | GPR3 (0.43) | KMT2AGAAGPR3MEN1LMNA | |
| SCHEMBL27549930 | 0.72 | GPR3 (0.42) | KMT2AGAAGPR3MEN1LMNA | |
| SCHEMBL28494353 | 0.72 | POLB (0.41) | KMT2AGAAGPR3POLBMAPT | |
| SCHEMBL4600049 | 0.71 | GPR3 (0.41) | KMT2AGAAGPR3POLBMAPT | |
| SCHEMBL1830100 | 0.71 | GPR3 (0.41) | KMT2AGAAGPR3MEN1LMNA | |
| SCHEMBL31355068 | 0.71 | GPR3 (0.41) | KMT2AGAAGPR3POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005028449-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF 1,2-DISUBSTITUTED HEXAHYDROPYRIDAZINE-3-CARBOXYLIC ACIDS AND ESTERS THEREOF | HONEYWELL SPECIALTY CHEMICALS SEELZE GMBH (DE) | 2005-03-31 | — | — | WO | disclosed |