Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29202280 | 0.80 | GPR3 (0.50) | GPR3KMT2APOLBHDAC3HDAC4 | |
| SCHEMBL17456836 | 0.78 | GPR3 (0.44) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL27819079 | 0.77 | GPR3 (0.43) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL6187729 | 0.76 | GPR3 (0.40) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL6502792 | 0.76 | KMT2A (0.47) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL27549930 | 0.76 | GPR3 (0.42) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL4603276 | 0.74 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL31355068 | 0.74 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL30510362 | 0.74 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 | |
| SCHEMBL30510269 | 0.74 | GPR3 (0.41) | GPR3KMT2APOLBGAAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160404-B1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | VALORISATION RECHERCHE LTD PARTNERSHIP (CA) | 2016-08-24 | — | — | EP | disclosed |
| US-9115171-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2015-08-25 | — | — | US | disclosed |
| US-20130203686-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | INSERM (FR) | 2013-08-08 | — | — | US | disclosed |
| US-8435954-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2013-05-07 | — | — | US | disclosed |
| US-20100210566-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE) (FR) | 2010-08-19 | — | — | US | disclosed |
| EP-2160404-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008154738-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | UNIVERSITE DE MONTREAL (CA) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130203686-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | MSR1, ASGR1, SCARB1 | GPR3 468/4885KMT2A 1958/4885POLB 2269/4885 |
| US-20100210566-A1 | AZAPEPTIDES AS CD36 BINDING COMPOUNDS | GHRHR, GHSR, GNRHR | GPR3 230/4885KMT2A 2301/4885POLB 3608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.